Type 2 diabetic nephropathy
Conditions
Interventions
Experimental group:Qidan Tangshen granule, Valsartan simulator
Control group:Qidan Tangshen granule simulator, Valsartan
Sponsors
LongHua Hospital Shanghai University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1.Meet the diagnostic criteria of diabetic kidney disease; 2.Type 2 diabetes; 3.Voluntarily participate in the clinical trial, give informed consent and sign informed consent; 4.TCM syndrome differentiation of qi deficiency and blood stasis; 5.Aged between 18 and 75 (including 18 and 75), with no gender limitation; 6.90/60 mmHg <= blood pressure <= 140/90 mmHg, and ACEI and ARB antihypertensive drugs are not used in the antihypertensive scheme; 7.Fasting blood glucose < 7.8 mmol/L, random blood glucose < 16.9 mmol/L, glycated hemoglobin < 9%, and SGLT2 and GLP-1 hypoglycemic drugs are not used in the hypoglycemic scheme.
Exclusion criteria
Exclusion criteria: 1.All kinds of primary kidney disease or secondary kidney disease except diabetic kidney disease; 2.At baseline, ALT or AST >= 1.5 times the upper limit of normal reference value, or hemoglobin <= 90 g/L; 3.Patients with acute infectious diseases, active and delayed stage of chronic viral hepatitis B, decompensated stage of cirrhosis and active stage tuberculosis, heart failure, cardiovascular accidents, trauma, surgery, urinary tract obstruction, renal artery stenosis, renal congenital malformation, after nephrectomy, etc.; 4.Patients who have used systemic sex hormones, immunosuppressants or renal replacement therapy in the past 3 months or currently need these treatment; 5.Allergic constitution, pregnant or lactating women; 6.Patients enrolled in other clinical trials within the last 3 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Glomerular filtration rate;Urinary albumin/creatinine;TCM syndromes and tongue and pulse; | — |
Secondary
| Measure | Time frame |
|---|---|
| Glycosylated hemoglobin;Fasting plasma glucose;Blood glucose 2 hours after meal; | — |
Countries
China
Contacts
Public ContactHua Yang
LongHua Hospital Shanghai University of Traditional Chinese Medicine
Outcome results
None listed