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Application of individualized intervention under target hemodynamics in laparoscopic surgery for elderly patients with coronary heart disease

Application of individualized intervention under target hemodynamics in laparoscopic surgery for elderly patients with coronary heart disease

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200056000
Enrollment
Unknown
Registered
2022-01-30
Start date
2022-01-27
Completion date
Unknown
Last updated
2024-07-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Laparoscopic surgery

Interventions

Dexmedetomidine group:Dexmedetomidine
control group:blank control

Sponsors

Nanxishan Hospital of Guangxi Zhuang Autonomous Region
Lead Sponsor

Eligibility

Sex/Gender
All
Age
60 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Patients who meet the diagnostic criteria of coronary heart disease; 2. Determined preoperative ECG myocardial ischemia; 3. Contains two or more risk factors for coronary heart disease: age >= 70 years,diabetes mellitus requiring treatment (oral antidiabetic medications or insulin), arterial hypertension, history of stroke, high cholesterol, smoking history (greater than 10 years), and abnormal ECG (signs of left ventricular hypertrophy, left bundle branch block); 4. With above more than two or more items, can be included in the trial.

Exclusion criteria

Exclusion criteria: 1. History of acute myocardial infarction, congestive cardiac insufficiency, acute coronary syndrome, and unstable angina within 6 months; 2. Severe hypertension (systolic blood pressure >= 180mmHg or mean blood pressure >= 110mmHg), or severe hypotension (systolic blood pressure < 90mmHg); 3. Combined with sinus bradycardia sinus node dysfunction atrioventricular block or sick sinus syndrome; 4. Complicated with severe COPD and bronchial asthma; 5. Complicated with immune system diseases, infectious diseases, severe liver and kidney dysfunction; 6. Concomitant coagulation dysfunction, or preoperative anemia (Hb < 90g/L).

Design outcomes

Primary

MeasureTime frame
hs-cTnT;inflammatory factor;Major Adverse Cardiovascular Events, MACE;

Secondary

MeasureTime frame
arterial blood gas analysis;Hemodynamic index;

Countries

China

Contacts

Public ContactLi Yuanqiang

Nanxishan Hospital of Guangxi Zhuang Autonomous Region

67443434@qq.com+86 15078348351

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026