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Clinical study of DNA methylation markers in noninvasive screening of endometrial cancer

Clinical study of DNA methylation markers in noninvasive screening of endometrial cancer

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2200055991
Enrollment
Unknown
Registered
2022-01-30
Start date
2022-02-01
Completion date
Unknown
Last updated
2024-07-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

endometrial cancer

Interventions

Sponsors

International Peace Maternity and Child Health Hospital, Shanghai Jiaotong University School of Medicine
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Test group: 1. Females aged 18 years and over, with a history of sexual life and not during pregnancy; 2. Patients with one of the following symptoms, clinically suspected endometrial cancer or atypical endometrial hyperplasia, and patients who will undergo endometrial biopsy in this medical institution: (1) Abnormal uterine bleeding (AUB); (2) Imaging findings of postmenopausal endometrial thickening (>= 5mm); (3) Imaging suggests intrauterine space occupying; (4) Patients with Lynch syndrome; (5) The doctor suspects endometrial cancer due to abnormal other physical signs, family history, genetics and other factors; 3. No history of other malignant tumors. Interference group: 1. Aged 18 years and over; 2. Pathological diagnosis of non-endometrial cancer, such as cervical cancer, ovarian (fallopian tube) cancer, breast cancer, uterine sarcoma, etc.

Exclusion criteria

Exclusion criteria: 1. Incomplete medical record information (including gender, age and other information and other demographic data, etc.); 2. Those who do not meet the requirements for sample collection and preservation.

Design outcomes

Primary

MeasureTime frame
DNA methylation;

Countries

China

Contacts

Public ContactWang Yudong

International Peace Maternity and Child Health Hospital, Shanghai Jiaotong University School of Medicine

owangyudong@126.com+86 18017316053

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026