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Effect of LRM and PEEP on Lung and Hemodynamics in Patients Undergoing Laparoscopic Radical Rectal Cancer Surgery

Effects of the Degree of Trendelenburg Angles on Brain Function in Patients Undergoing Laparoscopic Surgery

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200055989
Enrollment
Unknown
Registered
2022-01-30
Start date
2022-02-01
Completion date
Unknown
Last updated
2023-07-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Laparoscopic abdominal surgery

Interventions

NOLS group:Low tide volume ventilation
OLS group:Low tide ventilation
Fifteen minutes after induction of anesthesia, PATIENTS in the OLS group underwent LRM, repeated every 30 minutes, and individualized PEEP was set according to maximum lung compliance

Sponsors

The First Affiliated Hospital of Zhengzhou University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
50 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Aged 18 to 65 years; 2. ASA grade I - II; 3. BMI: 18-30.

Exclusion criteria

Exclusion criteria: 1.Intraoperative conversion to open operation 2.Severe allergic, cardiac arrest, massive bleeding and other adverse events occurred during the operation 3.Postoperative transfer to ICU

Design outcomes

Primary

MeasureTime frame
MAP;HR;CO;VT;Ppeak;Pplat;?P;PaO2;PaCO2;Number of cases and duration of intraoperative hypotension;Number of cases and dosage of vasoactive drugs;Atelectasis score;PPCs;—

Countries

China

Contacts

Public ContactSun Zhentao

The First Affiliated Hospital of Zhengzhou University

gentlesun@126.com+86 15736737328

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026