The effect of preoperative proton pump inhibitor use on postoperative complications after gastric endoscopic submucosal dissection: A randomized, controlled, multicenter, prospective study

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2200055982

Enrollment

Unknown

Registered

2022-01-30

Start date

2022-03-01

Completion date

Unknown

Last updated

2024-07-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

gastric endoscopic submucosal dissection

Interventions

test group:Intravenous infusion of standard-dose PPI on the morning of ESD

Control group:intravenous infusion of NS on the morning of ESD

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Aged 18 years and over; 2. Patients receiving gastric ESD.

Exclusion criteria

Exclusion criteria: 1. Have taken PPI preparations and antithrombotic drugs within 1 week before enrollment; 2. Have previously suffered from gastric cancer, diabetes, decompensated liver cirrhosis, tuberculosis, uremia, coagulation dysfunction, severe autoimmunity; 3. Those who are pregnant; 4. Those who are allergic to PPI preparations.

Design outcomes

Primary

Measure	Time frame
bleeding after ESD;Perforation after ESD;	—

Secondary

Measure	Time frame
hospitalization time;	—

Countries

China

Contacts

Public ContactChen Bin

Yuebei People's Hospital

ybcb333@163.com+86 13600218083

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026