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Prognostic value of quantitative EEG monitoring on brain function in patients with type A aortic dissection

Prognostic value of quantitative EEG monitoring on brain function in patients with type A aortic dissection

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2200055980
Enrollment
Unknown
Registered
2022-01-30
Start date
2022-02-01
Completion date
Unknown
Last updated
2024-07-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

type A aortic dissection

Interventions

Gold Standard:Clinical outcome
Index test:quantitative EEG monitoring

Sponsors

Nanjing Drum Tower Hospital, Chinese Academy of Medical Science & Peking Union Medical College
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Patients with type A aortic dissection and undergoing aortic surgery; 2. Males and females aged 18 years or above; 3. Subjects with the ability to read and understand the consent form.

Exclusion criteria

Exclusion criteria: Previous neurological and psychiatric history, cerebral infarction within half a year, pregnancy, malignant tumor, extremely moribund patients with an expected life expectancy of fewer than 24 hours.

Design outcomes

Primary

MeasureTime frame
Stroke;Delirium;Preoperative quantitative EEG monitoring (F3-P3);Preoperative quantitative EEG monitoring (F4-P4);Quantitative EEG monitoring after anesthesia induction (F3-P3);Quantitative EEG monitoring after anesthesia induction (F4-P4);Quantitative EEG monitoring after cardiopulmonary bypass (F3-P3);Quantitative EEG monitoring after cardiopulmonary bypass (F4-P4);Quantitative EEG monitoring after deep hypothermic circulatory arrest (F3-P3);Quantitative EEG monitoring after deep hypothermic circulatory arrest (F4-P4);Quantitative EEG monitoring after rewarming (F3-P3);Quantitative EEG monitoring after rewarming (F4-P4);Quantitative EEG monitoring (F3-P3) within 1h after entering ICU;Quantitative EEG monitoring (F4-P4) within 1h after entering ICU;Quantitative EEG monitoring (F3-P3) 1st day of postoperation;Quantitative EEG monitoring (F4-P4) 1st day of postoperation;Quantitative EEG monitoring (F3-P3) 2nd day of postoperation;Quantitative EEG monitoring (F4-P4) 2nd day of postoperation;Quantitative EEG monitoring (F3-P3) 3rd day of postoperation;Brain function assessment;Brain function assessment;Brain function assessment;Brain function assessment;Quality of life (SF-36);Quality of life (SF-36);Quality of life (SF-36);Quality of life (SF-36);Time of postoperative revival;

Secondary

MeasureTime frame
Respiratory related complications;All cause mortality;NSE;S100ß;CRP;TNFa;IL-6;IL-1a;IL-2;C3;C4;BNP;Measure the diameter of optic nerve sheath diameter;Measure pupil diameter;

Countries

China

Contacts

Public ContactWang Dongjin

Nanjing Drum Tower Hospital, Chinese Academy of Medical Science & Peking Union Medical College

dongjin_wang@126.com+86 13915980346

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Jun 26, 2026