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The Association of Coronary Calcification and Coronary Microcirculation in Patients with Heart Failure

The Association of Coronary Calcification and Coronary Microcirculation in Patients with Heart Failure

Status
Recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2200055969
Enrollment
Unknown
Registered
2022-01-30
Start date
2020-10-22
Completion date
Unknown
Last updated
2024-07-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Heart Failure

Interventions

Risk control:None
Healthy control:None

Sponsors

The First Affiliated Hospital of Sun Yat-sen University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1.Patients diagnosed with heart failure according to the current guidelines, and treated with medications regularly;(n=25) 2.Patients without cardiovascular disease but with controllable cardiovascular risk factors, such as hypertension, dyslipidemia, and diabetes;(n=25) 3.Healthy individuals aged 35 years or over, non-smoker, without cardiovascular disease or risk factor;(n=25) 4.Signed the informed consent.

Exclusion criteria

Exclusion criteria: 1.Allergic or contraindicated to ultrasound contrast agent; 2.Other serious cerebrovascular events, such as stroke or transient ischemic attack, have occurred within the last three months; 3.Patients with malignant tumors or multiple organ failure that may not have long-term survival; 4.Suffer from cognitive dysfunction, substance dependence, or severe mental illness; 5.Intravenous drug addicts; 6.Pregnant or lactating women, or planning to be pregnant or donate eggs during study period; 7.The researcher deems it inappropriate to participate in the clinical trial for any reason.

Design outcomes

Primary

MeasureTime frame
myocardial blood flow, MBF;coronary calcification;

Countries

China

Contacts

Public ContactDONG YUGANG, WEI FANGFEI

The First Affiliated Hospital of Sun Yat-sen University

fangfeimuxiang@163.com+86 13672468116

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026