polycystic ovary syndrome
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Non-pregnant Chinese women of reproductive age (20-34 years old) who were diagnosed with PCOS in the department of gynecology of our hospital and planned to get pregnant within one year; 2. Do not smoke or drink alcohol; 3. No periodontal treatment within 12 months; 4. Healthy except for oral and obstetric conditions, without systemic diseases (see exclusion criteria); 5. No antibiotics for at least the last three months.
Exclusion criteria
Exclusion criteria: 1. Those who took antibiotics within 3 months; 2. Received professional periodontal treatment (except for supringival plaque removal) within 12 months; 3. Not in good general health (other systemic diseases such as diabetes, cardiovascular disease, cancer, infectious diseases such as AIDS, hepatitis B, syphilis, rheumatic immune system diseases, etc.) before being diagnosed with PCOS; 4. After diagnosis of PCOS, the patient had other systemic complications in addition to metabolic complications; 5. Those who have received assisted reproductive technology; 6. Unwilling to participate in the study; 7. Continuous use of immunosuppressants, bisphosphonates for osteoporosis, or steroids and other hormones and immune-related drugs.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| PCOS and related treatments;Periodontal status;Sex hormones;Lipid levels;fasting insulin;Fasting plasma glucose;Early pregnancy; | — |
Secondary
| Measure | Time frame |
|---|---|
| Demographic characteristics;Lifestyles;History of gestation;Psychological health;cytokines and chemokines;Follicular development; | — |
Countries
China
Contacts
Shenzhen Maternity and Child Healthcare Hospital