The study of correlation and related functions of gut microbiome in perioperative period of congenital heart disease

The study of changes and related functions of perioperative gut microbiome in children with severe congenital heart disease

Status

Recruiting

Phases

Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2200055944

Enrollment

Unknown

Registered

2022-01-28

Start date

2019-11-01

Completion date

Unknown

Last updated

2023-07-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

congenital heart disease

Interventions

Probiotic group:Probiotic supplements

Eligibility

Sex/Gender

All

Age

1 Years to 18 Years

Inclusion criteria

Inclusion criteria: Children who meet the diagnostic criteria for severe congenital heart disease and can undergo primary correction surgery

Exclusion criteria

Exclusion criteria: (1)Children with ongenital heart disease combined with other systemic serious diseases such as esophageal atresia, trisomy 21, etc.(2)Children with immune disease(3)Premature infants with gestational age <37 W(4)Neonatal hemolysis;(5)Children who want palliative surgery

Design outcomes

Primary

Measure	Time frame
Distribution of gut microbiome;Changes in metabolites in urine;Immune factors in serum;developmental quotient;Brain development index;Nutritional development index;Cardiopulmonary function index;Gastrointestinal Function Index;	—

Countries

China

Contacts

Public ContactXuming Mo

Children's Hospital of Nanjing Medical University

mohsuming15@sina.com+86 18951769006

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026