cardiovascular health
Conditions
Interventions
four :Maintain balance in different postures on the Swiss ball
two:Balance on the Swiss ball
Sponsors
Capital University of Physical Education and Sports
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Aged 18 years over; 2. The subject has no history of organ disease and drug allergy, no history of drug abuse, smoking or alcoholism; 3. Physical examination, laboratory examination, 12-lead electrocardiogram and vital signs examination were judged as healthy subjects by the researcher; 4. No prescription drugs, over-the-counter drugs, or proprietary Chinese medicines were used 2 weeks before the test.
Exclusion criteria
Exclusion criteria: 1. Those who are allergic to bosentan or any ingredients in its excipients, or take vitamin C (VC), vitamin E and other antioxidant drugs; 2. Smoking, alcohol abuse, excessive drinking of strong tea, coffee and caffeinated beverages during the 6 months before screening and during the trial; 3. Have a history of prescription drug abuse and illegal drug abuse within 6 months before screening; 4. Subjects who are participating in other clinical trials; 5. Researchers believe that other reasons are not suitable for clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cardio-ankle vascular index;heart rate variability;Nitric oxide;endothelin-1;ROS;SOD;MDA;TAC;GPX; | — |
Countries
China
Contacts
Public ContactZhu Weili
Capital University of Physical Education and Sports
Outcome results
None listed