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Effect of perioperative intravenous lidocaine on postoperative recovery after radical surgery for advanced colon cancer: A prospective, randomized, double-blind, placebo-controlled pilot trial

Effect of perioperative intravenous lidocaine on postoperative recovery after radical surgery for advanced colon cancer: A prospective, randomized, double-blind, placebo-controlled pilot trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200055937
Enrollment
Unknown
Registered
2022-01-26
Start date
2022-02-11
Completion date
Unknown
Last updated
2024-07-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Outcomes of advanced colon cancer surgery

Interventions

lidocaine:lidocaine
Placebo:normal saline

Sponsors

The First Affiliated Hospital of Soochow University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Aged 18 years or over; 2. ASA status I-III; 3. Scheduled to undergo elective radical surgery for advanced colon cancer under general anesthesia.

Exclusion criteria

Exclusion criteria: 1. Previous or concurrent malignancy; 2. History of myocardial infarction or cerebrovascular accident; 3. Renal failure; 4. Liver insufficiency; 5. Epilepsy; 6. Heart block; 7. Allergy to lidocaine.

Design outcomes

Primary

MeasureTime frame
Plasma concentration of lidocaine;—

Secondary

MeasureTime frame
Recovery from surgery;—

Countries

China

Contacts

Public ContactPeng Ke

The First Affiliated Hospital of Soochow University

pengke0422@163.com+86 159 6215 5989

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026