mechanical ventilation during craniotomy
Conditions
Interventions
Driving pressure group:Driving pressure–guided PEEP
Control group:Conventional VCV
Sponsors
The First Affiliated Hospital of Soochow University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Patients aged 18 years and over, regardless of gender; 2. ASA physical status I to III; 3. Scheduled for elective craniotomy under general anesthesia; 4. BMI 18-30kg/m^2; 5. Clearly understand the experimental process, volunteer to participate in this study, and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Severe cardiovascular diseases, renal or liver dysfunction; 2. Severe pulmonary diseases, ARDS, bronchopleural fistula, pneumothorax; 3. High intracranial pressure; 4. Refusal for participation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Brain relaxation score;Blood loss; | — |
Secondary
| Measure | Time frame |
|---|---|
| Oxygenation index;Incidence of significant postoperative pulmonary complications (PPCS);Severity of PPCS;ARDS;Atelectasis;Pneumonia;Hypoxemia;Pneumothorax;Pleural effusion;ICU admission;Bleeding; | — |
Countries
China
Contacts
Public ContactJi Fuhai
The First Affiliated Hospital of Soochow University
Outcome results
None listed