schizophrenia
Conditions
Interventions
Intervention group:Digital cognitive function training
Control group:Regular treatment
Sponsors
Peking Universality Sixth Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 50 Years
Inclusion criteria
Inclusion criteria: 1. Diagnosis of schizophrenia according to DSM-5 criteria; 2. Aged 18-50 years; 3. Course of disease <=5 years; 4. Can understand the content of informed consent and research process, and sign informed consent; 5. There was no significant drug adjustment in 2 months, and no plan of drug adjustment in the next 6 months; 6. Evidence of no symptom fluctuation 2 months before enrollment: no hospitalization for schizophrenia, no increase in treatment due to disease aggravation; 7. PANSS score: P1 (delusion), P2 (conceptual disorder), P3 (hallucination), N1 (emotional retardation), N4 (social withdrawal), N6 (lack of spontaneity and fluency in conversation), G5 (affectation and posturing), G9 (abnormal thinking content) <= 3 points.
Exclusion criteria
Exclusion criteria: 1. Pre-existing or current diseases that may affect cognitive function, including but not limited to mental retardation, dementia, alcohol or other substance dependence, head trauma with loss of consciousness for more than 1 hour, etc.; 2. Currently taking methylphenidate, anti-dementia drugs, amphetamine, lithium salts, monoamine oxidase inhibitors, tricyclic antidepressants; 3. Currently taking first-generation antipsychotic drugs or clozapine; 4. There is a risk of suicide (suicidal behavior in the past 1 year, suicidal idea or attempt in the past 3 months); 5. She had received MECT or rTMS in the last 6 months; 6. There are contraindications to MRI, such as pacemaker and nerve stimulator, metal in the body, etc.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| MRI; | — |
Countries
China
Contacts
Public ContactShi Chuan
Peking Universality Sixth Hospital
Outcome results
None listed