Perioperative hypotension
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Aged 45 years and over; 2. Moderate or high-risk noncardiac surgery (gastrointestinal surgery, hepatobiliary surgery, urology surgery, esophagectomy, pneumonectomy, lung or liver transplantation); 3. General anesthesia; 4. Surgery duration expected to last >= 2 hours from skin incision; 5. Planned postoperative hospitalization >= 3 days; 6. Written informed consent.
Exclusion criteria
Exclusion criteria: 1. Participating in another interventional study; 2. Receiving low-risk surgery only (for example, superficial surgery, breast surgery, thyroid surgery, minor plastic surgery, transurethral resection of the prostate); 3. Confirmed to be pregnant and/or nursing mothers; 4. Emergency surgery; 5. Having severe comorbidities (clinically important intra-cardiac shunts, aortic stenosis with valve area <= 1.5 cm^2, moderate to severe aortic regurgitation, moderate to severe mitral regurgitation, moderate to severe mitral stenosis, persistent atrial fibrillation, acute congestive heart failure); 6. Previously receiving heart valve surgery, coronary artery bypass grafting, percutaneous coronary intervention, pacemaker implantation, or ICD implantation; 7. Patient in whom an intraoperative mean arterial pressure target will be < 65 mmHg (including controlled hypotension); 8. With an intra-aortic balloon pump (IABP) or ventricular assist device(s); 9. Requiring multiple vasoactive agents and known diagnosis of ongoing active sepsis.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Perioperative hypotension subtypes; | — |
Countries
China
Contacts
The First Affiliated Hospital, Sun Yat-sen University