Acute ischemic stroke
Conditions
Interventions
treatment group:Edaravone and Dexborneol Concentrated Solution for Injection +Recanalization therapy(Intravenous thrombolysis / intravascular therapy)
Control group:conventional therapy +Recanalization therapy(Intravenous thrombolysis / intravascular therapy)
Sponsors
Putian First Hospital, Fujian Province
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1.Aged 18 to 80 years; 2.Stroke diagnosis determined by the Fourth Academic Conference on cerebrovascular diseases in 1995 Standard, combined with clinical symptoms and imaging examination; 3.Onset time < 48 hours; 4.Meet the indications of intravenous thrombolysis and receive intravenous thrombolysis; Or cranial CTA or MRA or DSA showed obstruction of large blood vessels (ICA, mca-m1, ACA, PCA, BA) and received intravascular intervention; 5.6 <= NIHSS score <= 25; 6.mRS score before onset <= 1; 7.The patient/family member signed the informed consent form.
Exclusion criteria
Exclusion criteria: 1.Previous mental illness or cognitive impairment, unable to live normally or cooperate with the researcher; 2.Contraindication of Edaravone and right camphor; 3.Those who refuse or cannot effectively cooperate with the treatment; 4.Other unwilling to participate in the research.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The rate of good prognosis after 90 days.(mRs=2); | — |
Secondary
| Measure | Time frame |
|---|---|
| Changes of plasma inflammation markers; | — |
Countries
China
Contacts
Public ContactChen Ping
Putian First Hospital, Fujian Province
Outcome results
None listed