IgA nephropathy
Conditions
Interventions
"eficiency of spleen and lung qi" group:none
"deficiency of Qi and Yin" group:none
Sponsors
Chinese PLA General Hosptial
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Patients with primary IgA nephropathy diagnosed by renal biopsy after January 2000; 2. EGFR >= 15ml / Min1.73? in renal biopsy; 3. Aged over 18 years old (including 18 years old) at the time of renal biopsy, regardless of gender; 4. There are four diagnostic information records of traditional Chinese medicine. The syndrome differentiation of traditional Chinese medicine belongs to "deficiency of spleen and lung qi" or "deficiency of Qi and Yin"; 5. Meet the definition of high-risk IgA nephropathy patients in kdigo2020 guidelines (urinary protein is still > 1g / d after optimized support treatment for at least 90 days).
Exclusion criteria
Exclusion criteria: 1. Secondary IgA nephropathy such as purpura nephritis, lupus nephritis and hepatitis B; 2. Other renal diseases such as membranous nephropathy; 3. Combined with diabetes, connective tissue disease and other systemic diseases.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| All-cause mortality or initiation of maintenance renal replacement therapy; | — |
Secondary
| Measure | Time frame |
|---|---|
| decrease of eGFR >= 50%;Clinical remission (3 consecutive drops in urinary protein within 6 months to < 0.3g/d with stable creatinine); | — |
Countries
China
Contacts
Public ContactDuan Shuwei
Chinese PLA General Hosptial
Outcome results
None listed