non-alcoholic fatty liver and periodontal disease
Conditions
Interventions
Test group:Subgingival scaling and root planing+ IDisinfection of inner wall of pocket by Er,Cr:YSGG
Control group:Enhanced brushing
Sponsors
Shanghai Jiao Tong University School of Medicine Shanghai Ninth People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. According to the medical history, clinical examination, and laboratory examination, who was diagnosed as non-alcoholic fatty liver patients; 2. Suffered from moderate or severe periodontitis, did not receive periodontal treatment.
Exclusion criteria
Exclusion criteria: 1. Having a history of severe drinking; 2. Recent history of drug using related to non-alcoholic fatty liver; 3. Other chronic liver disease; 4. Other systemic disease and infectious diseases; 5. Pregnant.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Alanine transaminase;The number of porphyromonas gingivals;Serum lgG antibody titer for porphyromonas;Probing bleeding percentage;Clinical attachment level;Probing depth;Liver stiffness;Lipid biomarker;Liver fat content;Blood index of liver function;Body mass index;Blood endotoxin activity;Non-alcohol fatty liver related blood inflammation index;Type ? collagen;blood glucose?insulin?homeostasis modal insulin resistance index;Full mouth plaque score;Salivary melatonin levels;Fibrosis 4 Score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Full mouth plaque score; | — |
Countries
China
Contacts
Public ContactWang Yuhua
Shanghai Jiao Tong University School of Medicine Shanghai Ninth People's Hospital
Outcome results
None listed