Covert hepatic encephalopathy
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients with clinically confirmed cirrhosis; 2. Aged 18 to 75, with no gender limitation; 3. No OHE at present: MMSE >25.
Exclusion criteria
Exclusion criteria: 1.The presence of other uncontrollable neuropsychiatric diseases or neurological diseases that affect cognitive function, such as Alzheimer's disease, Parkinson's disease, schizophrenia, etc.; 2.Taking hypnotic or sedative drugs or psychotropic drugs in the past 4 weeks; 3.Men who consumed alcohol in the past 3 months >20g/ day, female > 10g/ day; 4.Other conditions that cannot complete the test independently, such as red-green color blindness, inability to read and write, difficulty in understanding, etc.; 5.The researcher thinks it is not suitable for participants.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Influencing factors of covert hepatic encephalopathy;Prevalence of CHE in cirrhotic patients; | — |
Secondary
| Measure | Time frame |
|---|---|
| Proportion of CHE screened by SNS method in patients with cirrhosis;quality of life;The time taken by the investigator/study nurse and the patient to complete the PHES and App Stroop test, SDS, respectively; | — |
Countries
China
Contacts
Changzheng Hospital affiliated to PLA Naval Military Medical University