Skip to content

Investigation on the prevalence of covert hepatic encephalopathy in Chinese cirrhotic patients and validation study of SNS test in the diagnosis of covert hepatic encephalopathy

Investigation on the prevalence of covert hepatic encephalopathy in Chinese cirrhotic patients and validation study of SNS test in the diagnosis of covert hepatic encephalopathy

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2200055895
Enrollment
Unknown
Registered
2022-01-22
Start date
2020-07-01
Completion date
Unknown
Last updated
2023-07-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Covert hepatic encephalopathy

Interventions

Case series:None

Sponsors

Changzheng Hospital affiliated to PLA Naval Military Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Patients with clinically confirmed cirrhosis; 2. Aged 18 to 75, with no gender limitation; 3. No OHE at present: MMSE >25.

Exclusion criteria

Exclusion criteria: 1.The presence of other uncontrollable neuropsychiatric diseases or neurological diseases that affect cognitive function, such as Alzheimer's disease, Parkinson's disease, schizophrenia, etc.; 2.Taking hypnotic or sedative drugs or psychotropic drugs in the past 4 weeks; 3.Men who consumed alcohol in the past 3 months >20g/ day, female > 10g/ day; 4.Other conditions that cannot complete the test independently, such as red-green color blindness, inability to read and write, difficulty in understanding, etc.; 5.The researcher thinks it is not suitable for participants.

Design outcomes

Primary

MeasureTime frame
Influencing factors of covert hepatic encephalopathy;Prevalence of CHE in cirrhotic patients;

Secondary

MeasureTime frame
Proportion of CHE screened by SNS method in patients with cirrhosis;quality of life;The time taken by the investigator/study nurse and the patient to complete the PHES and App Stroop test, SDS, respectively;

Countries

China

Contacts

Public ContactXie Weifen

Changzheng Hospital affiliated to PLA Naval Military Medical University

weifenxie@medmail.com+86 13701682806

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026