Acute ischemic stroke
Conditions
Interventions
Study group:Operated according to the ECASES system
Control group :Operated according to operator experience
Sponsors
Tianjin Huanhu Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1.Age 18-80 years old, regardless of gender. 2.Preoperative NIHSS score = 6. 3.An ASPECTS score of =6 based on MRI-DWI sequences. 4.The time from onset to the expected start of endovascular treatment was =24 hours, with patients between 6 and 16 hours meeting the inclusion criteria for the DAWN study and the DEFUSE 3 study, and patients between 16 and 24 hours meeting the inclusion criteria for the DAWN study. 5.Pre-stroke MRS score of 0-1. 6.Life expectancy = 2 years. 7.Patients and their families agreed to the endovascular treatment and this study protocol and signed an informed consent form.
Exclusion criteria
Exclusion criteria: 1.Patients with combined intracranial hemorrhage confirmed by CT or MRI are excluded. 2.Patients with a combination of severe renal insufficiency (creatinine > 264 µmol/L), respiratory and circulatory instability, severe coagulation dysfunction (INR > 3.0 or PTT > 3 times normal) and other contraindications to interventional procedures are excluded. 3.Patients with pre-existing neurological or psychiatric disorders that could confound the evaluation of the results were excluded. 4.Uncontrollable hypertension Systolic blood pressure >185 mmHg Diastolic blood pressure >110 mmHg. 5.Platelet count 22.20 mmol/L. 7.Those who cannot undergo cranial MRI. 8.Patients deemed unsuitable for study participation by other investigators.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| NIHSS score;mRS score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Changes in neurological function;Intracranial hemorrhage;Cerebral edema;mTICI grading;New cerebral infarction;Reocclusion of the responsible vessel; | — |
Countries
China
Contacts
Public ContactHecheng Ren
Tianjin Huanhu Hospital
Outcome results
None listed