stroke
Conditions
Interventions
Experiment group:Conventional cognition rehabilitation training + NeuCir-VR group
Control group:Conventional rehabilitation training + VR group
Sponsors
Shanghai University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Patients diagnosed with stroke by clinical assessment and comprehensive imaging examination met the diagnostic criteria for stroke; 2. Cognitive impairment confirmed by MMSE and daily behavior dysfunction confirmed by ADL scale; 3. Aged 18 to 75 years, no gender limit; 4. No cognitive impairment or communication impairment, with a mini-mental state examination (MMSE) score of 27 or more; 5. The first onset, the duration of the disease was less than 6 months; 6. Chinese as the first language, primary school education or above, able to complete the assessment.
Exclusion criteria
Exclusion criteria: 1.Those who have serious systemic diseases such as cardiopulmonary disease and cannot tolerate rehabilitation treatment; 2.Patients with diagnosed psychosis, major depression (suicidal tendency) or epilepsy, and those with a family history of psychosis or epilepsy; 3.There are influencing factors of serious systemic diseases such as diabetes and uremia; 4.Suffer from any cause of consciousness disorder; 5.Those who cannot complete the neuropsychological examination due to severe aphasia or physical disability; 6.People with a history of alcoholism, or drug addiction, or neurological diseases such as brain trauma, epilepsy, encephalitis, normal intracranial pressure and hydrocephalus that can cause cognitive impairment; 7.Suffer from systemic diseases that may cause mild cognitive impairment (such as liver and kidney dysfunction, endocrine diseases, vitamin deficiency); 8.According to the safety guidelines, there are contraindications for transcranial direct current/magnetic stimulation (TMS/tDCS) and functional magnetic resonance (fMRI) examinations such as metal foreign bodies in the body or other electronic devices implanted in the body, etc.; 9.Defects in hearing or vision may affect assessment and virtual reality rehabilitation; 10.Use drugs that change the excitability of the cerebral cortex (antiepileptic drugs, sedative, and hypnotic drugs, etc.);
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Montreal Cognitive Assessment (MoCA); | — |
Secondary
| Measure | Time frame |
|---|---|
| mini-mental state examination;Clinical Dementia Rating;Alzheimer’s disease assessment scale,ADAS-cog;Executive Function Performance Test;Visual space capability assessment;daily activities ability;functional magnetic resonance imaging (fMRI);Neuroelectrophysiological feedback; | — |
Countries
China
Contacts
Public ContactXu Jianguang
Shanghai University of Traditional Chinese Medicine
Outcome results
None listed