A prospective, cohort study of the clinical outcomes and risk factors of progression in conservative treatment of penetrating aortic ulcer and intermural hematoma

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2200055865

Enrollment

Unknown

Registered

2022-01-21

Start date

2022-02-15

Completion date

Unknown

Last updated

2023-07-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

penetrating aortic ulcer and intermural hematoma

Interventions

PAU and IMH patients:none

Eligibility

Sex/Gender

All

Age

18 Years to 90 Years

Inclusion criteria

Inclusion criteria: 1. Male or female aged 18 years and over; 2. The CTA results of our hospital clearly diagnosed Pau or IMH. The depth of Pau was < 10mm, the width was < 20mm, the thickness of IMH was < 15mm, and the maximum diameter of aorta was < 50mm; 3. CTA showed no complication of AD and / or aortic aneurysm at the time of diagnosis.

Exclusion criteria

Exclusion criteria: 1. Patients with lesions located in the ascending aorta; 2. Hemodynamic instability or obvious tendency of aortic rupture at the initial diagnosis; 3. Contrast medium allergy, severe renal failure (creatinine > 250 umol / L), pregnant women and other reasons can not be examined by CTA; 4. Unable to sign informed consent; 5. Patients with life expectancy < 2 years.

Design outcomes

Primary

Measure	Time frame
Surgical intervention;	—

Secondary

Measure	Time frame
Aorta-related mortality;All-cause mortality;	—

Countries

China

Contacts

Public ContactDong Zhihui

Zhongshan Hospital, Fudan University

dzh926@126.com+86 13564249168

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026