Renal cell carcinoma
Conditions
Interventions
positive MRD:None
negative MRD:None
Sponsors
Chinese PLA General Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1.Patients with high risk of recurrence who can receive radical nephrectomy; 2.Clinical stage: T2N0M0, T1/2N1M0,T3N0/1M0, T4N0/1M0; 3.Negative margin and there was no tumor residue; 4.The histopathological types of renal carcinoma are not limited: clear cell carcinoma and non-clear cell carcinoma; 5.Agree to provide archived tumor tissue samples or fresh tissue samples (tissue samples must be available) and blood samples at different time points; 6.ECOG PS Score of 0 to 2 points; 7.The expected survival is greater than 6 months; 8.Aged 18 to 80 years old; 9.Willing to sign informed consent; 10.Patients were able to follow up regularly, communicate well with the investigator, and complete the study according to study guidelines.
Exclusion criteria
Exclusion criteria: 1.Positive margin or residual lesions were found; 2.A patient with a prior history of other malignancies may not participate in the study unless he/she has been in complete remission for at least 5 years prior to enrollment and does not require other treatment or does not require other treatment during the study period; 3.Associated with serious medical conditions, including but not limited to uncontrolled diabetes, active gastrointestinal ulcers, active bleeding, etc; 4.Sample collection and preservation methods are not standardized; 5.Incomplete information about subjects; 6.Patients with insufficient communication, understanding, and cooperation, or poor compliance to ensure that follow-up is completed as required; 7.The investigator considers that subjects who are not suitable to participate in this clinical study for various other reasons will withdraw from the study or terminate the study treatment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| disease-free survival; | — |
Secondary
| Measure | Time frame |
|---|---|
| overall survival; | — |
Countries
China
Contacts
Public ContactZhang Xu
Chinese PLA General Hospital
Outcome results
None listed