Dentition Defect
Conditions
Interventions
Test group:One Ibuprofen Sustained Release Capsule will be taken orally 15 minutes before operation
Sponsors
Beijing Stomatological Hospital, Capital Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 50 Years
Inclusion criteria
Inclusion criteria: 1.The age range is 18 to 50 years; 2.No history of cardiopulmonary disease, liver and kidney disease, abnormal bleeding and abnormal coagulation function; 3.No analgesic, anti-inflammatory and anticoagulant drugs were taken 1 week before operation; 4.A single maxillary or mandibular posterior tooth needs to be implanted without guided tissue regeneration, maxillary sinus lifting, etc; 5.Cone beam computed tomography confirmed that the implant site had sufficient bone width and bone height; 6.The operation is expected to be completed within 15-30 minutes; 7.Patients are willing to participate in this study and fill in the questionnaire.
Exclusion criteria
Exclusion criteria: 1.Pregnant, physiological or lactating women; 2.Combined with acute oral infectious diseases or tumors; 3.Allergic reaction to the drug used in this study; 4.Suffering from chronic pulpitis, chronic periapical periodontitis, trigeminal neuralgia, glossopharyngeal neuralgia and other pain diseases without treatment or requiring long-term use of other painkillers; 5.The patient drank alcohol within one week before operation; 6.Patients with previous history of upper gastrointestinal bleeding or perforation related to the use of nonsteroidal anti-inflammatory drugs; 7.Patients with active or previous history of peptic ulcer, gastrointestinal bleeding or perforation; 8.Allergic to other non steroidal anti-inflammatory drugs; 9.Asthmatic patients allergic to aspirin; 10.Taking other anti-inflammatory drugs containing ibuprofen or other non steroidal drugs, including drugs known to be specific cyclooxygenase-2 inhibitors; 11.Patients with intellectual, visual, hearing or communication impairment or other patients considered by the investigator to be unsuitable to participate in the trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| VAS score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Score of Dental Fear Survey (DFS);Score of Stouthard's Dental Anxiety Inventory (DAI);Dosage and duration of postoperative analgesics;Adverse reaction;VAS score; | — |
Countries
China
Contacts
Public ContactZhou Jian
Beijing Stomatological Hospital, Capital Medical University
Outcome results
None listed