Liver cancer
Conditions
Interventions
Gold Standard:High-throughput sequencing of tissues
Index test:Circulating tumor cell
Sponsors
The Sixth People's Hospital Affiliated to Shanghai Jiaotong University
Eligibility
Sex/Gender
All
Age
18 Years to 90 Years
Inclusion criteria
Inclusion criteria: 1.Patients with liver cancer who have been identified by imaging diagnosis after multidisciplinary discussion have no history of anti-tumor-related treatment such as surgery, radiotherapy or chemotherapy; 2.Age >= 18 years old; 3.There are measurable or evaluable tumor lesions by CT or MRI (according to RECIST 1.1 standard); 4.KPS score is greater than 60; 5.Good blood function: hemoglobin >= 8g/dL, absolute neutrophil count >= 1.5x10^9/L, platelet count >= 100x10^9/L; 6.Good liver and kidney function reserve: Child-Pugh class A liver function, creatinine clearance rate> 60 ml/min; creatinine <120 µmol/L; 7.No heart failure, no uncontrollable chest pain; no myocardial infarction or cerebral infarction occurred in the 12 months before the start of the study; 8.Sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1.No pathological evidence of liver cancer; 2.Patients suffering from other malignant tumors in the past; 3.Active infection period or other serious infections that may interfere with the test results of this project; 4.Patients with severe anemia or other organ dysfunction; 5.Pregnant or breastfeeding women; 6.Individuals who are undergoing correction monitoring or custody; 7.Other conditions that may interfere with the test results of this item.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Gene mutation; | — |
Secondary
| Measure | Time frame |
|---|---|
| Circulating tumor cell; | — |
Countries
China
Contacts
Public ContactHuang Xiuyan
The Sixth People's Hospital Affiliated to Shanghai Jiaotong University
Outcome results
None listed