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To compare the effects of ionomycin and strontium chloride on embryo outcome in patients with failed fertilization following intracytoplasmic sperm injection

To compare the effects of ionomycin and strontium chloride on embryo outcome in patients with failed fertilization following intracytoplasmic sperm injection

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200055839
Enrollment
Unknown
Registered
2022-01-20
Start date
2020-10-01
Completion date
Unknown
Last updated
2023-07-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients with repeated fertilization failure in assisted reproductive technology

Interventions

Strontium chloride group:AOA using strontium chloride
Lonomycin group:AOA using ionomycin
Strontium chloride and ionomycin group:AOA using strontium chloride and ionomycin

Sponsors

Shengjing Hospital of China Medical University
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 40 Years

Inclusion criteria

Inclusion criteria: 1. Fresh in vitro fertilization (IVF) cycles; 2. Fertilization failure following ICSI previously: fertilization rate = 9.

Exclusion criteria

Exclusion criteria: 1. Premature ovarian failure; 2. Oocytes with smooth endoplasmic reticulum aggregates.

Design outcomes

Primary

MeasureTime frame
Fertilization rate;—

Secondary

MeasureTime frame
Good quality day-3 embryos;—

Countries

China

Contacts

Public ContactLi Da

Shengjing Hospital of China Medical University

leeda@sina.cn+86 18940252099

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 9, 2026