Rheumatoid arthritis
Conditions
Interventions
Test group:Eilamod
control group:Traditional DMARDs
Sponsors
Weihai Municipal Hospital, Cheeloo College of Medicine, Shandong University
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18 to 60 years(to the date of screening), inclusive; both male and female; 2. Weight not less than 40kg; 3. The pregnancy test of female subjects was negative; Agree to use effective contraceptives during the trial; 4. Patients with moderate and high activity RA who meet the RA diagnostic criteria launched by ACR in 1987 or ACR \ EULAR in 2010, i.e. DAS28 >= 3.2.
Exclusion criteria
Exclusion criteria: 1. Combined with other rheumatic diseases; 2. Complicated with other organ serious diseases; 3. There are active infectious diseases or chronic infectious diseases; 4. Patients with mental disorders, alcoholism, immune deficiency, uncontrolled infection, drug or other substance abusers; 5. Subjects received live vaccine within 6 weeks or planned to use any live vaccine during the study period; 6. Patients using biological agents; 7. Patients with joint replacement or / and joint trauma; 8. Patients with previous osteoporosis or osteoporosis related treatment; 9. Various other conditions that researchers believe cannot be included in this clinical observation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Bone metabolism index;Musculoskeletal ultrasound score;Bone mineral density test; | — |
Countries
China
Contacts
Public ContactZhang Jian
Weihai Municipal Hospital, Cheeloo College of Medicine, Shandong University
Outcome results
None listed