Skip to content

The mucoperiosteum-bone flap operation with bone and frame preservation versus traditional curettage operation without bone preservation for the treatment of jaw cystic lesion: A randomized, parallel controlled clinical trial

Clinical trial of bone flap with the mucoperiosteum and traditional curettage operation in the treatment of jaw cystic lesion

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200055830
Enrollment
Unknown
Registered
2022-01-20
Start date
2022-02-07
Completion date
Unknown
Last updated
2023-08-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Oral Surgery

Interventions

The control group:Traditional curettage operation without bone preservation
The experimental group:The mucoperiosteum-bone flap operation with bone and frame preservation

Sponsors

School of Stomatology, The Fourth Military Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
12 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. CBCT showed that the boundary of maxillary cystic lesions was clear and the smallest diameter was >= 15mm, the shadow area was uniform, and the cyst was completely or mostly covered by bone of lip/buccal or lingual/palatal side, and was diagnosed as jaw cyst by assisted puncture examination; 2. Patients had no systemic diseases, good compliance and timely review(1d,3d,7d,1m,3m,6m), and could tolerate surgery; 3. Aged from 12 to 60 years.

Exclusion criteria

Exclusion criteria: 1. Patients with systemic diseases, which affectted bone healing and bone regeneration, had a history of bisphosphonates and a history of radiotherapy and chemotherapy within six months; 2. Patients with incomplete clinical data, poor compliance, were unable to return visit on time, and were unwilling to participate in the study; 3. Heavy smokers and alcoholics, pregnant women who could not accept radiographic examination, malignant tumors, moderate and severe heart disease, liver and kidney diseases, uncontrolled diabetes, blood diseases and coagulation dysfunction and other systemic diseases.

Design outcomes

Primary

MeasureTime frame
Osteogenesis ratio (percentage change of bone cavity volume/surface area/gray value);

Secondary

MeasureTime frame
Duration of operation/surgery time;VAS score for pain;postoperative swelling;maximum mouth opening;Volume of concentrated growth factor(CGF);Changed percentage of volume/surface area of air cavity;Infection rate;Anxiety and fear level;Histopathology of cyst and bone specimens;Observing the surface morphology of free bone;

Countries

China

Contacts

Public ContactDeng Tiange

School of Stomatology, The Fourth Military Medical University (FMMU)

dtgyszc@163.com+86 153 5357 0431

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026