lung cancer
Conditions
Interventions
Central axis paravertebral block group (CAPVB group):Before the operation, the patients underwent thoracoscopy-guided axial paravertebral nerve block at T3 and T5 levels, each with 12.5ml of 0.5% ropi
Cost margin paravertebral nerve block group (CMPVB group):Before the operation, the patients underwent thoracoscopic-guided costal paravertebral nerve block at T3 and T5 levels, each with 12.5ml of 0.
Sponsors
Cancer Hospital, Chinese Academy of Medical Sciences
Eligibility
Sex/Gender
All
Age
20 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Aged 20 to 65 years; 2. American Society of Anesthesiologists Class I - III; 3. BMI: 18-25 kg/m2.
Exclusion criteria
Exclusion criteria: 1. Preoperative fever: axillary body temperature > 37.5 degree C on the day before surgery; 2. Patients with preoperative pulmonary ventilation dysfunction; 3. Patients with preoperative pulmonary infection, bronchial asthma or airway hyperresponsiveness; 4. History of previous thoracic surgery; 5. Pregnant women; 6. Patients with cardiac function class II or above; 7. Preoperative congenital heart disease, valvular disease, coronary heart disease, arrhythmia; 8. Central nervous system disease, History of stroke; 9. Complicated with hepatic insufficiency and renal insufficiency; 10. History of long-term chronic pain before surgery; 11. Those who have taken painkillers within 3 months before surgery.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The doses of opioid analgesics consumed by the patients were recorded at 24h and 48h after the operation; | — |
Secondary
| Measure | Time frame |
|---|---|
| Numerical rating scale (NRS) was used to evaluate the degree of acute pain of patients in the anesthesia recovery room (PACU), 6h, 12h, 18h, 24h, 36h, and 48h after surgery, immediately after the anesthesia was fully awake.;To measure the coverage and score of nerve block analgesia: (1) the area where the patient's skin pain was reduced after two different nerve block techniques were tested with plastic needles; (2) the pain score of the non-block site was 10 points as a reference, What is the pain score?;The time of first use of analgesics in the two groups after surgery;Postoperative doses of non-opioid analgesics in the two groups;Number of times sleep was interrupted by pain on the night of surgery;Incidence of postoperative analgesia-related adverse reactions, including postoperative respiratory depression, hypotension, nausea, vomiting, pruritus, etc.;In the two groups of patients, the time for the first time to get out of bed and walk independently for more than 10 steps after surgery; | — |
Countries
China
Contacts
Public ContactWang Qiang
Cancer Hospital, Chinese Academy of Medical Sciences
Outcome results
None listed