Ischemic Stroke
Conditions
Interventions
post-stroke cognitive impairment patients versus no PSCI people:N/A
Sponsors
Affiliated Dongguan Hospital, Southern Medical University (Dongguan People's Hospital)
Eligibility
Sex/Gender
All
Age
18 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1. The diagnosis of acute ischemic stroke meets the diagnostic criteria of 2018 Guidelines for Diagnosis and Treatment of Acute Ischemic Stroke in China and is confirmed by cerebral MRI; 2. Aged 18 to 85 years; 3. Patients with acute ischemic stroke of anterior circulation identified by transcranial brain MRI-DWI sequence; 4. The national institute of health stroke scale (NIHSS) was <= 15; 5. Modified RANKIN scale (mRS) <= 2 at discharge; 6. Patients or their families signed informed consent to participate in the study.
Exclusion criteria
Exclusion criteria: 1. Those who are complicated with serious physical diseases and other brain organic diseases can't cooperate; 2. With a history of dementia, mental disorder and severe depression, or present obvious cognitive dysfunction or severe depression; 3. Any mental disorders, personality disorders or psychoactive substance abuse or dependence; 4. Regular consumption of probiotics-containing drugs or drinks in the past month; 5. Antibiotics used in the last 3 months; 6. Severe diarrhea in the past 3 months (watery stools 3 or more times a day and lasting 3 or more days); 7. Severe constipation in the past 3 months (defecation twice a week or less with difficulty defecating); 8. Women during menstrual period, pregnant or lactating women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| MoCA score at 90 days; | — |
Secondary
| Measure | Time frame |
|---|---|
| Proportion of new clinical vascular events at 90 days;Proportion of patients with mRS score <= 2 at 90 days; | — |
Countries
China
Contacts
Public ContactLin Weifeng
Affiliated Dongguan Hospital, Southern Medical University (Dongguan People's Hospital)
Outcome results
None listed