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Influence of long-term exposure to atmospheric particulate pollution on the progression of Chronic Obstructive Pulmonary Disease

Influence of long-term exposure to atmospheric particulate pollution on the progression of Chronic Obstructive Pulmonary Disease

Status
Recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2200055750
Enrollment
Unknown
Registered
2022-01-17
Start date
2022-03-01
Completion date
Unknown
Last updated
2023-06-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic Obstructive Pulmonary Disease

Interventions

COPD patients:Nil

Sponsors

College of Environmental Sciences and Engineering, Peking University
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
55 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Male volunteers who had been diagnosed by a doctor with COPD, inclusion criteria for COPD patients were in line with the Global Initiative on Chronic Obstructive Pulmonary Disease (GOLD 2017) and the disease was stable at the time of inclusion; 2. Who aged 55 and above; 3. Who has lived within the sixth ring Road of Beijing for more than 3 years continuously, and has no plan to go out for more than half a year continuously during the survey period; 4. Who has medical records for three consecutive years or more; 5. Patients with COPD and asthma could be included.

Exclusion criteria

Exclusion criteria: 1. Patients with tumors, serious cardiovascular and cerebrovascular diseases, liver and kidney dysfunction, epilepsy and other neurological diseases and mental diseases or other diseases affecting the collection of information; 2. Who has had chest, abdominal or eye surgery in the last 3 months; 3. Who did not sign the informed consent.

Design outcomes

Primary

MeasureTime frame
atmospheric particles;atmospheric gaseous pollutants;lung function;6-minute walk test;heart rate variability;blood pressure;oxygen saturation;respiratory symptoms;inflammation;oxidative stress;blood routine;blood lipid;coagulation function;meteorological parameter;body mass index;Vascular elasticity index;Composition of exhaled condensate;fractional exhaled nitric oxide;

Countries

China

Contacts

Public ContactGong Jicheng

College of Environmental Sciences and Engineering, Peking University

jicheng.gong@pku.edu.cn+86 18600923276

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026