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Resting state fMRI-guided precise localization transcranial magnetic stimulation for patients with complex focal epilepsy

Resting state fMRI-guided precise localization transcranial magnetic stimulation for patients with complex focal epilepsy

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200055747
Enrollment
Unknown
Registered
2022-01-17
Start date
2022-01-31
Completion date
Unknown
Last updated
2023-06-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

epilepsy

Interventions

Sponsors

Center for Cognition and Brain Disorders, Affiliated Hospital of Hangzhou Normal University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. According to the International Alliance against Epilepsy (ILAE): failure to reduce the frequency of seizures to no more than four times per month is achieved with the use of at least two antiepileptic drugs for more than three months; 2. The patient had complex focal attacks and had not changed his/her medication regimen in the past 2 months.

Exclusion criteria

Exclusion criteria: 1. Patients with a history of extensive structural damage, stroke, and encephalitis; 2. Patients with other neurological and psychiatric disorders and who did not consistently take medication; 3. Patients who could not receive MRI scan or had MRI contraindications; 4. Women who had a recent pregnancy plan or in perinatal period; 5. Patients consumed illicit drugs and heavy alcohol.

Design outcomes

Primary

MeasureTime frame
frequency of epileptic seizures;

Secondary

MeasureTime frame
number of spikes in EEG;

Countries

China

Contacts

Public ContactZang Yufeng

Deqing Hospital, Hangzhou Normal University

zangyf@hznu.edu.cn+86 18606517380

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026