epilepsy
Conditions
Interventions
Sponsors
Center for Cognitive and Brain Diseases, Affiliated Hospital of Hangzhou Normal University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients diagnosed as drug-resistant epilepsy according to the International Alliance against Epilepsy (ILAE): 1. Failure to reduce the frequency of seizures to no more than four times per month after taking at least two antiepileptic drugs for more than three months; 2. The frequency of spikes or slow-wave discharges in the epileptic stage was at least 3 or more per minute, and the patient did not change his medication regimen in the past 2 months.
Exclusion criteria
Exclusion criteria: 1. Patients with a history of extensive structural damage, stroke, and encephalitis; 2. Patients with other neurological and psychiatric disorders and who did not consistently take medication; 3. Patients who could not receive MRI scan or had MRI contraindications; 4. Women who had a recent pregnancy plan or in perinatal period; 5. Patients consumed illicit drugs and heavy alcohol.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| number of spikes in EEG; | — |
Countries
China
Contacts
Public ContactZang Yufeng
Deqing Hospital, Hangzhou Normal University
Outcome results
None listed