Effects of low-dose esketamine combined with butorphanol controlled intravenous analgesia on postoperative analgesia, early mood and stress response in patients with cesarean section

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2200055733

Enrollment

Unknown

Registered

2022-01-16

Start date

2022-01-12

Completion date

Unknown

Last updated

2023-06-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

postpartum depression

Interventions

experimental group:esticketamine

control group:Sufentanil

Eligibility

Sex/Gender

Female

Age

18 Years to 40 Years

Inclusion criteria

Inclusion criteria: 1. American Society of Anesthesiologists stage I - II; 2. Aged between 18 and 40 years; 3. Patients with intraspinal anesthesia receiving routine cesarean section; 4. Weight: 60-85kg; 5. Signed informed consent.

Exclusion criteria

Exclusion criteria: 1. There is a history of local anesthetic drug allergy; 2. Patients who are addicted to ketamine, opioids and other drugs; 3. Complicated with liver, kidney and other important organ dysfunction; 4. Abnormal coagulation function; 5. Patients suffering from pregnancy hypertension, preeclampsia, eclampsia and other diseases.

Design outcomes

Primary

Measure	Time frame
Anxiety indicators;Depression;pain;sedation;inflammation;	—

Countries

China

Contacts

Public ContactYing Zhang

The Affiliated TCM Hospital of Southwest Medical University

zhangying021210@163.com+86 198 8179 5529

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026