Application of hybrid blood purification for septic patients

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2200055732

Enrollment

Unknown

Registered

2022-01-16

Start date

2019-10-01

Completion date

Unknown

Last updated

2023-06-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

sepsis,acute kidney injury

Interventions

hybrid CRRT group:oXiris filter for CRRT

control group:CVVH

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Diagnosis of Septic shock; 2. Any culture (such as blood, sputum, or drainage fluid) positive for bacteria or suspected to be caused by a Gram-negative agent; 3. Diagnosis of Stage 3 AKI.

Exclusion criteria

Exclusion criteria: 1. Patient aged < 18 years; 2. Weight <= 30kg; 3. Patients with highly contagious infectious diseases such as open tuberculosis; 4. Previous renal replacement therapy; 5. Patients that underwent cardio-pulmonary resuscitation (CPR).

Design outcomes

Primary

Measure	Time frame
survival or death;	—

Secondary

Measure	Time frame
length of stay ICU;length of stay;	—

Countries

China

Contacts

Public ContactMingli Zhu

Renji Hospital, Shanghai Jiao Tong University School of Medicine

millionzhu525@126.com+86 13701903155

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 11, 2026