nasopharyngeal carcinoma
Conditions
Interventions
case series:Nil
Sponsors
Sun Yat-sen University Cancer Center
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Patients with newly diagnosed stage III-IV nasopharyngeal carcinoma confirmed by histopathology and imaging, who receive concurrent radiotherapy and chemotherapy; 2. Aged 18-70 years (inclusive); 3. Physical function status KPS score >= 70 points; 4. The patient's lung, liver, kidney function, blood picture, and urine routine are within the agreed range (inclusion criteria in CRF), and the electrocardiogram must be within the normal range; 5. No other radiotherapy sensitizers were used in combination with Ximena during radiotherapy; 6. The use of Ximena radiotherapy sensitization cases has ended; 7. No other tumor diseases in the past, except for cured cervical carcinoma in situ, skin basal cancer or malignant diseases cured for 5 years; 8. Without AIDS, active tuberculosis and other serious immune abnormal diseases; 9. The radiotherapy technique adopts intensity-modulated radiation therapy; 10. The treatment plan is induction chemotherapy + concurrent chemoradiotherapy/concurrent chemoradiotherapy; 11. Complete treatment and follow-up data.
Exclusion criteria
Exclusion criteria: 1. Serious, uncontrolled diseases and infections; 2. History of active hepatitis; 3. Some obvious diseases that the researcher believes should be excluded from this study; 4. Other patients who are not considered suitable for inclusion in this study by the investigator.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Overall survival; | — |
Secondary
| Measure | Time frame |
|---|---|
| Objective mitigation rate ;Progression-free survival ;No distant metastasis for survival;No local recurrence of the survival period;Total irradiation dose at total and partial remission; | — |
Countries
China
Contacts
Public ContactYunfei Xia
Sun Yat-sen University Cancer Center
Outcome results
None listed