coronary heart disease
Conditions
Interventions
Sponsors
Capital Medical University Affiliated Beijing Anzhen Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18–80 years; 2. Primary diagnosis of NSTE-ACS or SIHD and appropriate candidates for isolated CABG; 3. Written informed consent before CABG surgery and ability to understand the nature of the study and the study-related procedures and to comply with them; 4. Undergoing CE-CABG.
Exclusion criteria
Exclusion criteria: 1. Severe congestive heart failure (NYHA class IV) or a left ventricular ejection fraction = 5, the operator needs to anastomosis the graft again. If PI is still >= 5 after excluding the influence of operation techniques, the operation is considered to have failed and the patient will be excluded; 13. More than 150 mL volume of the tube bleeding within 2 hours after surgery; 14. New-onset abnormal Q wave in the ECG within 2 hours after surgery; 15. Unable to complete the study or not comply with the requirements of the study (due to management or other reasons) according to the judgment of the investigators.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the cumulative tube drainage within 24 hours;The incidence of major adverse cardiovascular and cerebrovascular events in the two groups within 30 days after operation, including all-cause death, nonfatal myocardial infarction, nonfatal stroke and revascularization; | — |
Secondary
| Measure | Time frame |
|---|---|
| All cause mortality within 30 days after operation in both groups;The incidence of nonfatal myocardial infarction in the two groups within 30 days after operation;The incidence of nonfatal stroke in the two groups within 30 days after operation;The incidence of revascularization in the two groups within 30 days after operation;Postoperative renal insufficiency (serum creatinine level >= 200 µG/L, requiring acute hemodialysis, blood creatinine greater than twice the preoperative value);UDPB >= 3 within 24 hours;the incidence of TIMI major bleeding within 30 days; | — |
Countries
China
Contacts
Public ContactYang Yu
Capital Medical University Affiliated Beijing Anzhen Hospital
Outcome results
None listed