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Correction of cleft lip and palate nasal deformities with autologous chondrocyte regeneration and strength enhanced tissue engineered cartilage

Correction of cleft lip and palate nasal deformities with autologous chondrocyte regeneration and strength enhanced tissue engineered cartilage

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200055690
Enrollment
Unknown
Registered
2022-01-16
Start date
2021-06-01
Completion date
Unknown
Last updated
2023-06-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative cleft lip and palate deformities of plastic

Interventions

Group 1 :Tissue engineered cartilage fills the collapse of the nose

Sponsors

Shanghai Ninth People’s Hospital, Shanghai JiaoTong University School of Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 50 Years

Inclusion criteria

Inclusion criteria: 1. The first diagnosis must be consistent with cleft lip and palate deformity; 2. Age 18-50 years old; 3. Good health, no systemic diseases and infectious diseases in the past.

Exclusion criteria

Exclusion criteria: 1. Poor general condition; 2. Insufficiency of heart, lung, brain, kidney and other vital organs; 3. Blood disease or bleeding tendency; 4. Drug addiction (including drug, anesthetic and alcohol addiction); 5. Contagious virus infection; 6. Patients with systemic or local infection lesions; 7. Women who are pregnant or breastfeeding; 8. Have a mental illness and cannot cooperate with rehabilitation treatment; 9. Those with abnormal development of important organs or other organs; 10. Patients who are participating in other technical clinical application projects.

Design outcomes

Primary

MeasureTime frame
CT 3D reconstruction;Three dimensional laser scanning;

Secondary

MeasureTime frame
blood routine examination;C-reactive protein;Maxillofacial infection;General picture;

Countries

China

Contacts

Public ContactZhou Guangdong

Shanghai Ninth People’s Hospital, Shanghai Jiao Tong University School of Medicine

guangdongzhou@126.com+86 13818248439

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026