colorectal cancer
Conditions
Interventions
Control group:Intravenous infusion of equal volume of normal saline
Sponsors
The First People's Hospital of Changde
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Volunteer to participate in this study and have full capacity for civil conduct, and sign the informed consent; 2. Patients who undergo elective laparoscopic radical resection of colorectal cancer in our hospital; 3. Age 18-70 years old, BMI 18-30 kg/m2; 4. Operation time <= 3 hours; 5. The patient has not participated in other drug clinical trials in the past 3 months before enrollment.
Exclusion criteria
Exclusion criteria: 1. Patients who are allergic to lidocaine or amides; 2. Combined with other important organ dysfunction: including severe liver and kidney dysfunction; brain organic disease, specifically aneurysmal vascular disease or arteriovenous malformation and cerebral hemorrhage; severe hypertension, coronary heart disease, cardiac insufficiency (NYHA >= Grade III), pulmonary hypertension; blood system disease; abnormal coagulation function; severe respiratory system disease; 3. Patients with indoor conduction block; 4. Patients with untreated or undertreated hyperthyroidism; 5. Patients with alcohol or drug dependence or drug abuse history; 6. Patients with epilepsy, mental illness and taking antipsychotic drugs or family hereditary mental illness; 7. People with serious infectious diseases; 8. Other researchers think that they are not suitable for enrollment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Interleukin 6;Interleukin 8;Interleukin-1a;Tumor necrosis factor alpha; | — |
Countries
China
Contacts
Public ContactWang Xianxue
The First People's Hospital of Changde
Outcome results
None listed