Knee osteoarthritis
Conditions
Interventions
Experimental group:prolotherapy + active tDCS
Control group:prolotherapy + sham tDCS
Sponsors
The Affiliated Hospital of Qingdao University
Eligibility
Sex/Gender
All
Age
40 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. According to the clinical and radiological standards established by the American College of Rheumatology, if it meets the following A+B or A+C+E+F; A+D+E+F, it can be diagnosed as KOA (A: recurrent knee pain within the last 1 month; B: X-ray film (standing or weight-bearing position) shows narrowing of joint space, subchondral sclerosis (or) cystic degeneration, and osteophyte formation at the joint margin; C: typical synovium of osteoarthritis Effusion: clear, viscous, WBC = 40 years old); E: morning stiffness <= 30 min; F: bone friction rub when moving); 2. Patients who voluntarily received intra-articular injections and tdcs.
Exclusion criteria
Exclusion criteria: 1. Diseased knee joint with local skin infection, joint tumor or tuberculosis; 2. Previous history of knee surgery or injection therapy in or around the knee joint within the past 3 months; 3. Severe underlying diseases and coagulation disorders; 4. History of brain surgery, brain tumor, epilepsy, stroke or intracranial metal implantation; 5. Participants who are combined with cognitive impairment and mental disorder and cannot cooperate with treatment and follow-up will be excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Visual Analog Scale/Score;The Western Ontario and McMaster Universities Osteoarthritis Index;Pressure pain thresholds;Conditioned Pain Modulation; | — |
Countries
China
Contacts
Public ContactLi Tieshan
The Affiliated Hospital of Qingdao University
Outcome results
None listed