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Effects of intraoperative methylprednisolone and dexamethasone on the incidence and prognosis of postoperative nausea and vomiting in patients undergoing general anesthesia

Effects of intraoperative methylprednisolone and dexamethasone on the incidence and prognosis of postoperative nausea and vomiting in patients undergoing general anesthesia

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200055643
Enrollment
Unknown
Registered
2022-01-15
Start date
2022-01-10
Completion date
Unknown
Last updated
2023-02-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

PONV

Interventions

group A:2ml of saline was given intravenously during induction of anesthesia
Group B:Dexamethasone given during induction of anesthesia
GroupC:Methylprednisolone was given during induction of anesthesia

Sponsors

The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: Adult patients (over 18 years of age) undergoing surgical procedures under general anesthesia.

Exclusion criteria

Exclusion criteria: include: pregnant women, patients with a previous history of diabetes mellitus or whose preoperative tests indicate elevated fasting blood glucose levels, patients with active peptic ulcers, and patients who are taking hormonal medications prior to surgery.

Design outcomes

Primary

MeasureTime frame
Incidence of PONV;

Secondary

MeasureTime frame
FACIT-F SCALE;

Countries

China

Contacts

Public ContactMaoJiali
shiningmao96@sina.com+86 13865999759

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026