High myopia macular hole
Conditions
Interventions
experimental group:Retinal pigment epithelial cells are transplanted into the macular hole area
Sponsors
Chongqing Southwest Hospital Ophthalmology Department
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Volunteer as the subject, and the patient signs the informed consent; 2. Aged between 18 and 65 years, regardless of gender; 3. OCT examination confirmed the diagnosis of idiopathic macular hole; 4. Patients with large aperture (horizontal distance at the narrowest part of the hole > 700 µm) or patients with a long course of disease (duration >= 6 months) or those with previous retinal detachment repositioning or vitreous surgery.
Exclusion criteria
Exclusion criteria: 1. Patients with optic neuropathy, corneal disease, glaucoma, uveitis and other vitreoretinal diseases; 2. Combined with severe cardiovascular, liver, kidney and hematopoietic system and other primary diseases, mental illness; 3. Systemic or local use of other drugs that affect the evaluation of efficacy, such as glucocorticoids; 4. Pregnant and lactating women; 5. Those who have participated in other clinical trials in the past three months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Best corrected visual acuity;Intraocular Pressure;Fundus Photography;Spectral Domain Opticalcoherence Tomography, SD-OCT; | — |
Countries
China
Contacts
Public ContactYong Liu
Chongqing Southwest Hospital Ophthalmology Department
Outcome results
None listed