tongue squamous cell carcinoma
Conditions
Interventions
Experimental group:submental-submandibular dehiscence approach
Control group:Median split lower lip approach
Sponsors
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. The age of the patient on the day of signing the informed consent is 18 years old or above; 2. The pathological diagnosis is tongue squamous cell carcinoma; 3. The primary tumor size of tongue cancer is T2-T3, the preoperative clinical examination and imaging examination are negative for cervical lymph node (cN0), and the distant metastasis is M0; 4. There are no old scars and other lesions on the lower lip and chin; 5. The vital signs are stable, and the routine examination shows that the operation can be tolerated; 6. The patient is in good mental state, can follow the doctor's orders, and have regular follow-up visits; 7. Understand and be willing to participate in this clinical trial and provide signed informed consent.
Exclusion criteria
Exclusion criteria: 1. Pre-existing disease will affect wound healing (such as autoimmune disease); 2. Scar constitution; 3. Uncontrolled hyperglycemia (such as HbA1c > 12.0%); 4. Patients who need postoperative adjuvant radiotherapy/chemotherapy after consultation with radiotherapy physicians; 5. Those with severe uncontrolled disease or acute systemic infection, and those with other serious heart, lung, encephalopathy and other serious organ diseases; 6. Patients with psychiatric diseases; 7. Those who are considered inappropriate by the researchers to be included; 8. The patient participated in this study at any time in the past.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| University of Washington Quality of Life Questionnaire; | — |
Secondary
| Measure | Time frame |
|---|---|
| 3-year overall survival rate;3-year disease-free survival rate;Vancouver Scar Scale; | — |
Countries
China
Contacts
Public ContactWang Youyuan
Department of Oral and Maxillofacial Surgery, Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Outcome results
None listed