depression
Conditions
Interventions
Group A:Vitamin D Supplementation
Group B:Placebo
Sponsors
Hefei Fourth People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1.Participants are diagnosed with DSM-V and had definite diagnosis by two professional attending physicians; 2.Aged 18 to 65 years , had primary school and above education; 3.Serum 25(OH)D < 75 nmol/L.
Exclusion criteria
Exclusion criteria: 1.Diagnosed as schizophrenia, disorders caused by psychoactive substances and other mental diseases; 2.combined with neurological diseases, malignant tumors, cardiovascular diseases, respiratory diseases, severe trauma, pregnancy or lactation, etc.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Serum 25 (OH) D;High-sensitivity C-reactive protein;Brain network properties;Behavior Rating Inventory of Executive Function;Revised Social Anhedonia Scale Score;Revised Physical Anhedonia Scale,RPAS-C;Hamilton depression scale(HAMD-24) score;Hamilton Anxiety Rating Scale(HAMA-14) score;sleep;Aspartate aminotransferase;Alanine aminotransferase;Serum cholesterol concentration;Serum triglyceride concentration;Serum high density lipoprotein concentration;Thyroid function;Serum prolactin concentration;Social dysfunction scale score;Ability of daily living scale; | — |
Countries
China
Contacts
Public ContactZhu Daomin
Hefei Fourth People's Hospital
Outcome results
None listed