Mild hepatic encephalopathy
Conditions
Interventions
Case group:Nutritional risk score
Control group:Nutritional risk score
Sponsors
Affiliated Hospital of Qingdao University
Eligibility
Sex/Gender
All
Age
32 Years to 78 Years
Inclusion criteria
Inclusion criteria: 1.Patients with liver cirrhosis were diagnosed according to the 2019 guidelines for the diagnosis and treatment of liver cirrhosis.
Exclusion criteria
Exclusion criteria: 1. Patients with brain diseases such as cerebral hemorrhage, cerebral infarction, brain tumor, intracranial infection, epilepsy, metabolic encephalopathy such as ketoacidosis, hypoglycemia, renal encephalopathy, pulmonary encephalopathy, alcoholic encephalopathy, heavy metal toxic encephalopathy, abstinence syndrome and other toxic encephalopathy; 2. A patient with a history of mental illness; 3. Patients with dominant hepatic encephalopathy or previous history of dominant hepatic encephalopathy; 4. Patients with diabetes, severe cardiopulmonary disease, renal insufficiency, thyroid disease, intestinal obstruction, etc. other extrahepatic diseases that can lead to malnutrition and chronic diarrhea; patients with a history of gastrointestinal bleeding within 6 weeks; patients with persistent active infection; 5. Patients who had received Helicobacter pylori sterilization or antibiotics, lactulose, probiotics, PPI and gastrointestinal motility drugs such as mosapride and domperidone within two weeks; patients who had been tested by enema or colonoscopy within 1 month; 6. Patients who have undergone abdominal surgery such as gastrectomy and enterectomy; 7. Patients with hearing and visual impairment that are unable to undergo digital connection test and digital symbol test; 8. Patients with poor compliance and other factors that may affect the results of this experiment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| nutritional risk score;Blood sugar;Protein determination;Blood lipid analysis;Electrolyte determination;MELD score; | — |
Countries
China
Contacts
Public ContactCao Bin
Qingdao University
Outcome results
None listed