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The Effect of Chinese Patent Medicine Pai-Neng-Da Capsule Combination with Chemotherapy on Peripheral Blood Cell Count and Symptoms of Patients with B Cell non-Hodgkin’s Lymphoma:A Clinical Multi-Center Study

The Effect of Chinese Patent Medicine Pai-Neng-Da Capsule Combination with Chemotherapy on Peripheral Blood Cell Count and Symptoms of Patients with B Cell non-Hodgkin’s Lymphoma:A Clinical Multi-Center Study

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200055579
Enrollment
Unknown
Registered
2022-01-14
Start date
2016-01-01
Completion date
Unknown
Last updated
2023-02-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cell non-Hodgkin’s lymphoma

Interventions

Experimental group:R-CHOP-21 scheme + Pai-Neng-Da Capsule
Control group:R-CHOP-21 scheme

Sponsors

Lishui Central Municiple Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Those who meet the diagnostic criteria of western medicine for this disease and the diagnostic criteria of TCM deficiency syndrome. All cases were diagnosed as B-cell non-Hodgkin lymphoma by pathological examination and were treated with standard R-CHOP-21 chemotherapy; 2. Aged 18 to 70 years, male or female; 3. The expected survival period is more than 3 months; 4. Quality of life Karnofdky score >= 60 points 5. Blood routine (peripheral blood white blood cell count >= 3.5 × 10^9/L, neutrophil count >= 1.5 × 10^9/L, platelet count >= 100 × 10^9/L, hemoglobin >= 90 g/L); 6. Liver and kidney functions are basically normal. The electrocardiogram was normal. ^

Exclusion criteria

Exclusion criteria: 1. CD5-positive, EBV-positive B-cell lymphoma, pregnant or lactating women, or mentally ill patients; 2. Serum creatinine Cr > 1.5 mg/ml (133 µmol/L) or corrected creatinine clearance 2 times the upper limit of normal); 4. Known allergy to any test drug or drugs with the same chemical structure as the test drug; 5. Combined with any serious disease, which may affect the evaluation of the study; 6. The researchers considered patients with poor compliance, incomplete clinical data and lost patients; 7. Patients receiving radiotherapy at the same time.

Design outcomes

Primary

MeasureTime frame
peripheral blood cell count;T cell subsets;

Countries

China

Contacts

Public ContactLi LinJie

Lishui Central Municiple Hospital

lilinjie0394@163.com+86 13567615761

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026