diabetic foot ulcers
Conditions
Interventions
VAC group:No
Conventional moist dressings group:No
Sponsors
Nanjing First Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Patients with DFUs; 2. Aged 20-80 years; 3. Wagner stage 2 to 4, duration of disease >= 2 weeks; 4. Ankle brachial ratio (ABI) 0.5-0.9; 5. Wound area 2-20 cm2.
Exclusion criteria
Exclusion criteria: 1. Patients who were unable to complete the follow-up; 2. Pregnant or nursing mothers were not included; 3. Patients with foot ulcers other than diabetes; 4. Patients with heart dysfunction, liver dysfunction or kidney dysfunction, patients with malignant tumors or hematological diseases; 5. Patients with osteomyelitis, peripheral vascular disease, organ dysfunctions, or autoimmune diseases; 6. Patients who received growth factors or hyperbaric oxygen therapies for the DFUs wounds within one month; 7. Patients who had medications (such as corticosteroids, immunosuppressive agents or chemotherapy) within six months were not included; 8. Other patients who are not suitable for inclusion.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Time from first debridement to STSG surgery; | — |
Secondary
| Measure | Time frame |
|---|---|
| Wound blood perfusion;Neutrophil extracellular traps (NETs) formation;Percentages of M1 or M2 macrophages; | — |
Countries
China
Contacts
Public ContactWu Yin
Outcome results
None listed