treatment-resistant schizophrenia
Conditions
Interventions
case series:Nil
Sponsors
Huzhou Third People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. From October 2016 to December 2021, all outpatients or inpatients with schizophrenia who combined with or switched to blonanserin, regardless of age and gender; 2. It meets the diagnostic criteria of DSM-5 for schizophrenia; 3. It meets the diagnostic criteria of TRRIP working group for refractory schizophrenia; 4. PANSS >= 70 points, CGI-S >= 4 points; 5. Upon admission, the patient has signed the informed consent of medical record data for scientific research, or the patient or his family members have agreed to use his medical record data only for scientific research.
Exclusion criteria
Exclusion criteria: 1. Schizoid-affective disorder, dementia or other cognitive impairment, bipolar disorder, eating disorder, obsessive-compulsive disorder, panic disorder, etc. according to DSM-5 diagnosis, but the secondary related above symptoms are not included; 2. Diseases meeting DSM-5 diagnostic criteria: borderline, antisocial, paranoid, schizophrenic, schizophrenic or performance personality disorders, but secondary personality changes above are not included; 3. It was not due to poor curative effect or intolerance, but only due to economic conditions, it was forced to interrupt or stop the medicinal blonanserin within 2 weeks; 4. Those who received blonanserin treatment for less than 2 weeks and lost the follow-up; 5. Within 2 weeks after receiving blonanserin treatment, he also received rTMS, MECT and other physical therapy or clozapine treatment that may affect the efficacy evaluation of blonanserin.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The scores of 8 main items in PANSS=3; | — |
Secondary
| Measure | Time frame |
|---|---|
| the score of CGI-SI=3;the score of SOFAS >80; | — |
Countries
China
Contacts
Public ContactWang Shikai
Huzhou Third People's Hospital
Outcome results
None listed