gastric cancer
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Siewert type ? / ? esophagogastric junction carcinoma, cT1-2N0M0, tumor length <= 4 cm, longer abdominal esophagus; 2. Radical gastrectomy of proximal gastric cancer is required, and more than 1/2 of the distal remnant stomach can be preserved after resection; 3. Aged 18 to 75 years, regardless of gender, physical strength score ECOG <= 2 points, ASA <= 2 points, can tolerate surgical treatment, liver, kidney, bone marrow function normal; 4. Be able to comply with the protocol during the study and sign the informed consent; 5. Patients are willing to accept follow-up and cooperate with professional staff to make relevant records; 6. No history of gastrointestinal surgery, malignant tumor, chemotherapy or radiotherapy.
Exclusion criteria
Exclusion criteria: 1. Radical total gastrectomy is required; 2. SOFY or Kamikawa anastomosis is not suitable for esophagogastric junction carcinoma with tumor invasion of dentate line or large tumor range; 3. Patients with severe heart and lung disease who cannot tolerate surgery; 4. Patients who are unwilling to bear the risks of surgery and fail to sign the informed consent for surgery; 5. Uncontrollable medical diseases (including unstable angina pectoris, myocardial infarction and cerebrovascular accident within 6 months); 6. Unable to receive general anesthesia or surgery due to other organ conditions; 7. Have a history of uncontrolled epilepsy, central nervous system disease or mental disorder; 8. Organ transplantation requiring immunosuppressive therapy; 9. Serious and uncontrolled recurrent infection, or other serious and uncontrolled concomitant diseases; 10. Continuous systemic steroid hormone therapy; 11. Pregnant or lactating women of childbearing age; 12. Participate in other clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence of reflux after operation; | — |
Secondary
| Measure | Time frame |
|---|---|
| PGSAS-45 scores; | — |
Countries
China
Contacts
Beijing Friendship Hospital,Capital Medical University