Clinical Research on the Effect of Non-Surgical Disc Reduction for Condylar Repair and Regeneration in Early-stage Temporomandibular Joint Osteoarthritis

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2200055552

Enrollment

Unknown

Registered

2022-01-12

Start date

2020-06-01

Completion date

Unknown

Last updated

2023-02-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

temporomandibular joint osteoarthritis

Interventions

Experimental group:physical disc reduction combined with splint therapy

Control group:traditional conservative treatment

Eligibility

Sex/Gender

All

Age

12 Years to 30 Years

Inclusion criteria

Inclusion criteria: 1. Aged 12 to 30 years old; 2. Early osteoarthritis: CBCT shows surface erosion/destruction and/or cortical discontinuity; 3. Using DC / TMD diagnostic criteria and MRI, the patients were diagnosed with acute anterior disc displacement without reduction or anterior disc displacement with reduction; 4. Signed informed consent.

Exclusion criteria

Exclusion criteria: 1. Presence of systematic joint diseases (eg, rheumatoid arthritis); 2. Presence of acute synovitis or suppurative TMJ arthritis; 3. Systematic disorders; 4. Presence of psychological distress including anxiety and depression; 5. History of TMJ surgery.

Design outcomes

Primary

Measure	Time frame
qualitative assessment of condylar osseous changes;	—

Secondary

Measure	Time frame
mouth opening;joint pain;	—

Countries

China

Contacts

Public ContactLei Jie

Peking University School & Hospital of Stomatology

leijierebecca1986@163.com+86 15201304344

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026