Knee osteoarthritis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients requiring unilateral initial TKA surgery due to severe knee osteoarthritis; 2. Aged 18 to 80 years; 3. Body mass index 20~35 kg/m^2; 4. The American Society of Anesthesiologists (ASA) classification (anesthesia risk assessment) is I ~ III level.
Exclusion criteria
Exclusion criteria: 1. Allergic to anesthetic drugs and sulfa; 2. There were more than moderate intraoperative knee malformations (pronation and flexion malformations) and joint stiffness; 3. Alcoholic or long-term opioid users; 4. Language impairment and inability to perform the visual analogue scale(VAS); 5. Surgical limb neuropathy; 6. Mental patients; 7. Patients with previous gastrointestinal ulcer.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| VAS pain score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Range of knee motion;The duration of hospital stay; Incidence of postoperative complications;Gastrocnemius muscle strength; | — |
Countries
China
Contacts
Baoding First Central Hospital